Our lab in ES&T

Congratulations to Justine for having her undergraduate work published in Environmental Science & Technology (ES&T).

This study investigates the effects of the azo dye the Disperse Yellow 7 (DY7) in early developement in frogs and shows that high concentration of this dye in sediment induces mortality and malformation in larvae, and further molecular analysis shows that DY7 increases heat shock protein 70 and 90 mRNAs while a microarray investigation suggests that the dye also alters genes associated with necrotic cell death, chromosome condensation, and mRNA processing. Finally, the treatment also lead to change in androgen related gene expression.

Mathieu-Denoncourt J, Martyniuk CJ, de Solla SR, Balakrishnan  VK and VS Langlois. Sediment contaminated with the azo dye Disperse Yellow 7 alters cellular stress- and androgen-related transcription in Silurana tropicalis larvae. Environ Science Technol. In press LINK