Congrats to Sonja for her first Ph. D. 1st author paper!

Sonja developed an ex vivo protocol to assess the effects of chemicals when directly in contact to frog organs (brain, liver and testes) and she validated it using the human drug finasteride. Microarray analysis revealed that when testes are exposed to the drug, very interesting transcriptomics changes occur, including meiosis, hormone biosynthesis, sperm entry, gonadotropin releasing hormone, oxysterol synthesis, apoptosis, and epigenetic regulation.

Bissegger S, Martyniuk CJ and VS Langlois.  Transcriptomic response of finasteride in male frog gonads using an ex vivo approachGen Comp Endocrinol

Congrats Sonja! Well done! – Langlois Lab