Lab Crew 2016

oct-2016a

Back row: Barry Madison (PDF), Ftoon Alsaadi (M. Sc.), Linda Lara (Ph. D.), Dr. Langlois, Brianna Willard (B. Sc. H.), Alex Leclerc (B. Sc. H.), Christina Emerton (Technician), Sarah Wallace (Lab manager), and Denby McDonnell (B. Sc. H.). Front row: Lucie Baillon (PDF), Tash-Lynn Colson (M. Sc.), and Paisley Thomson (M. Sc.).

Two new studies on the effects of arsenic in frogs

We recently conducted acute and chronic arsenic exposures to frogs. In the acute exposures performed during early development, we have discovered that genes involved with signal transduction, cell survival, developmental pathways, and histone remodeling have their expression altered following arsenic exposure suggesting that AsV-treated animals are coping with the contaminated water in order to survive and continue their development.

Zhang J, Koch I, Gibson LA, Loughery JR, Martyniuk CJ, Button M, Caumette G, Reimer KJ, Cullen WR  and VS Langlois (2015) Transcriptomic responses during early development following arsenic exposure in Western clawed frogs, Silurana tropicalis. Tox Sci 148(2):603-17. ARTICLE

In the chronic exposures, endocrine disruption was observed in frogs exposed to environmentally relevant concentrations of AsV as transcripts related to reproduction and thyroid hormones varied among tissues and developmental stages analyzed.

Gibson L, Caumette G, Button M, Koch I Reimer KJ, Cullen WR  and VS Langlois (2016) Life cycle exposure of the frog Silurana tropicalis to arsenate: Steroid- and thyroid hormone-related genes are differently altered throughout development. Gen Comp Endocrinol doi: 10.1016/j.ygcen.2015.09.015. [Epub ahead of print] ARTICLE

IN THE NEWS: Study produced by my research group

B. Madison

Click here to see the Press Release

Dr. Langlois has been promoted to the rank of Associate Professor!

The effects of diluted bitumen (to be transported by pipelines) in fish

We have just published the first study investigating the biological effects of diluted bitumen which is to be transported by pipelines in fish (in case of oil spills). One of my post-doctoral students, Dr. Barry Madison, is the first author of this work.

For free download of the study (until August 14th, 2015): FREE ARTICLE

Madison BN, Hodson PV, Langlois VS. Diluted bitumen causes deformities and molecular responses indicative of oxidative stress in Japanese medaka embryos. Aquatic Toxicology. 2015 Jun 17; 165:222-230. doi: 10.1016/j.aquatox.2015.06.006. [Epub ahead of print] ARTICLE

New publication in Metallomics

We have recently published this collaborative piece of work in which we studied arsenic speciation and its effects on DNA methylation during frog metamorphosis. Two of my high qualified personnel: my post-doc Dr. Jing Zhang and a research assistant, Laura Gibson have contributed to this research paper.

Koch I, Zhang J, Button M, Gibson LA, Caumette G, Langlois VS, Reimer KJ, Cullen WR. Arsenic(+3) and DNA methyltransferases, and arsenic speciation in tadpole and frog life stages of western clawed frogs (Silurana tropicalis) exposed to arsenate. Metallomics. Jun 12. [Epub ahead of print] ARTICLE

The Governor General’s Gold Medal for one of M. Sc. students in my lab

The first grad student to have completed a thesis in my laboratory, Justine Mathieu-Denoncourt, has received the prestigious Governor General’s Gold Medal at the Spring convocation 2015. The Governor General’s Gold Medal is awarded to the graduating student who achieves the highest academic standing in a Master’s or Doctoral programme (http://www.rmcc.forces.gc.ca/aca/ac-pe/gsc-adc/sb-bep-9-eng.php). 

Congratulations Justine! You have produced an outstanding thesis! – Langlois Lab

A Canada Research Chair (CRC) for Dr. Langlois!

Dr. Langlois just got granted a tier II Canada Research Chair (CRC) in Ecotoxicogenomics and Endocrine Disruption.

Welcome to new lab members!

We wish to welcome two master students: Ftoon Alsaadi and Paisley Thomson, two NSERC-USRA students: Giselle Hunt and Marie Sereneo, and one summer work experience student: Steven Davis to our research group! – Langlois Lab

Public Lecture: How do aquatic animals cope with water contamination?

How do aquatic animals cope with water contamination?

by Dr. Langlois (RMCC)

Date: Friday, March 20 2015
Time: 6:00 pm
Location: Robert Sutherland Room 202 (on Queen’s University campus)
Free to the general public, as well as students and faculty at Queen’s and RMC