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Naphthalene sulfonic acids and salts (NSAs) are high volume chemicals used for a variety of applications, including: pesticides (fungicide, insecticide, microbiocide); lubricants; plasticizers; rust/corrosion inhibitors, and adhesive/sealants. NSAs are considered to be persistent, bioaccumulative, and inherently toxic. The proposed work aims to uncover the toxicity and the modes of action of NSAs in aquatic organisms using an ‘omics approach. Metabolomics compares the relative differences between biological samples based on their metabolite profiles, giving an instantaneous snapshot of the entire physiology of an organism. Among others, this project will combine metabolomics datasets with transcriptomics analysis to provide a more comprehensive understanding of the impacts of NSAs in aquatic species (i.e., amphibians and mussels).

A position for a doctoral student is available to assess the effects of up to four NSAs in aquatic species using an ecotoxicogenomics approach. The project funding is for 4 years, starting September 2016.  The principal laboratories are located at the Royal Military College of Canada (Kingston, ON, Canada), Queen’s University (Kingston, ON, Canada) and the Canada Center for Inland Waters (Burlington, ON, Canada).  The successful candidate will work in an extended research network comprising researchers from academia, Government of Canada, and industry.


  • M. Sc. in biochemistry, toxicology, physiology, or biology-related studies;
  • Demonstrated excellence in scientific achievement and publication;
  • Excellent oral and written communication skills;
  • Experience with animal physiology and transcriptomics and/or metabolomics;
  • Knowledge of LC-MS methods;
  • Skilled in aspects of analytical chemistry; and
  • Knowledge in bioinformatics would be an asset.

If interested, please send a letter of research interest, a CV, and the names and contact information of three referees to valerie.langlois@rmc.ca before April 22nd, 2016. 

For further information please contact:


Dr. Valerie Langlois

Canada Research Chair in Ecotoxicogenomics and Endocrine Disruption

Environmental Toxicology and Endocrinology (ETE) Laboratory

Dept. Chemistry & Chemical Engineering, Royal Military College of Canada



Dr. Vimal Balakrishnan

Aquatic Contaminants Research Division, Canada Center for Inland Waters

Environment and Climate Change Canada