Publications

Recent Scientific Publications

Names of mentored HQP are in bold. Names other than Langlois are of collaborators from academia (Canadian1 and International2) or government3.

Martin J1, Colson TL, Langlois VS and CD Metcalfe(2016) Biomarkers of exposure to nanosilver and silver accumulation in yellow perch (Perca flavescens). Environ Toxicol Chem [Epub ahead of print] ARTICLE

Bissegger S and VS Langlois (2016) Steroid 5-reductases are functional during early frog development and are regulated via DNA methylation. Mech Dev 141, 14-24. ARTICLE

Mathieu-Denoncourt J, Wallace SJ, de Solla SR3 and VS Langlois (2016) Influence of lipophilicity on the toxicity of bisphenol A and phthalates to aquatic organisms. Bull Environ Chem Tox 97(1):4-10. ARTICLE

Bissegger S and VS Langlois (2016) Androgens modulate gene expression and specific DNA methylation pattern of steroid 5α-reductases in the frog Silurana tropicalis. Gen Comp Endocrinol 234:123-132. ARTICLE

Mathieu-Denoncourt J, Martyniuk CJ2, Yargeau V1, de Solla SR3 and VS Langlois (2016) Lethal and sublethal effects of phthalate diesters on Silurana tropicalis larvae. Environ Toxicol Chem 97(1):4-10 ARTICLE

Crump D3, Farhat A3, Chiu S3, Williams KL3, Jones SP3 and VS Langlois (2016) Use of a novel double-crested cormorant ToxChip PCR array and the EROD assay to determine effects of environmental contaminants in primary hepatocytes. Environ Sci Technol 50(6):3265-3274.  ARTICLE

Gibson L, Caumette G1, Button M 1, Koch I1, Reimer KJ1, Cullen WR 1 and VS Langlois (2016) Life cycle exposure of the frog Silurana tropicalis to arsenate: Steroid- and thyroid hormone-related genes are differently altered throughout development. Gen Comp Endocrinol 234:133-141.  ARTICLE

Balakrishnan VK3, Shirin S3, Aman AM3, de Solla SR3, Mathieu-Denoncourt J and VS Langlois (2016) Genotoxic and carcinogenic products arising from reductive transformations of the azo dye, Disperse Yellow 7. Chemosphere 146: 206-215. ARTICLE

Zhang J, Koch I1, Gibson LA, Loughery JR1, Martyniuk CJ2, Button M1, Caumette G1, Reimer KJ1, Cullen WR 1 and VS Langlois (2015) Transcriptomic responses during early development following arsenic exposure in Western clawed frogs, Silurana tropicalis. Tox Sci 148(2):603-17. ARTICLE

Madison BN, Hodson PV1 and VS Langlois. Diluted bitumen causes deformities and molecular responses indicative of oxidative stress in Japanese medaka embryos. Aq Tox 165:222-230. doi: 10.1016/j.aquatox.2015.06.006. [Epub ahead of print] ARTICLE

Koch I1, Zhang J, Button M1, Gibson L, Caumette G1, Langlois VS, Reimer KJ1 and WR Cullen1. Arsenic(+3) and DNA methyltransferases and arsenic speciation in tadpole and frog life stages of Western Clawed frogs (Silurana tropicalis) exposed to arsenate. Metallomics Jun 12 2015 [Epub ahead of print] ARTICLE

Mathieu-Denoncourt J, de Solla SR3 and VS Langlois (2015) Chronic exposure to monomethyl phthalate alters metamorphosis and sex ratio in Western clawed frogs. Gen Comp Endocrinol doi: 10.1016/j.ygcen.2015.01.019. [Epub ahead of print] ARTICLE

Mathieu-Denoncourt J, de Solla SR3 and VS Langlois (2015) Plasticizer endocrine disruption: Highlighting developmental and reproductive effects in mammals and non-mammalian aquatic species. Gen Comp Endocrinol doi: 10.1016/j.ygcen.2014.11.003. [Epub ahead of print] OPEN ACCESS ARTICLE (FREE)

Castañeda DC, Langlois VS and JI Fernandino2 (2014) Crossover of the hypothalamic pituitary-adrenal/interrenal (HPA), -thyroid (HPT), and -gonadal (HPG) axes in testicular development Frontiers Endocrinol 5:139. ARTICLE

Zhang J, Carnduff L, Norman G, Josey T3, Wang Y3, Sawyer T3 Martyniuk CJ1 and VS Langlois (2014) Transcriptional profiling in rat hair follicles following simulated blast insult: A new diagnostic tool for traumatic brain injury. PLoS ONE 9(8): e104518. OPEN ACCESS ARTICLE (FREE)

Flood D and VS Langlois (2014)  Crosstalk between androgen and thyroid hormones during amphibian early development. Gen Comp Endocrinol 203:232-40. ARTICLE

Bissegger S, Martyniuk CJ1 and VS Langlois (2014)  Transcriptomic response of finasteride in male frog gonads using an ex vivo approach. Gen Comp Endocrinol 203:137-45. ARTICLE

Gibson LA, Lavoie RA1Bissegger S, Campbell LM 1 and VS Langlois (2014) A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood. Ecotoxicol 23(6):1004-14. ARTICLE

Mathieu-Denoncourt J, Martyniuk CJ1, de Solla SR3, Balakrishnan  VK3 and VS Langlois (2014) Sediment contaminated with the azo dye Disperse Yellow 7 alters cellular stress- and androgen-related transcription in Silurana tropicalis larvae. Environ Science Technol.  48(5):2952-61. ARTICLE

Soriano JJ, Mathieu-Denoncourt J, Norman G, de Solla SR3 and VS Langlois (2014).  Effects of Acid Red 97 and Bismack Brown Y in frog larvae development. Environ Sci Pollut Res. 21(5):3582-91ARTICLE

Martyniuk CJ1, Bissegger S and VS Langlois (2014)  Current perspectives on the androgen 5 alpha-dihydrotestosterone (DHT) and 5 alpha-reductases in teleost fishes and amphibians. Gen Comp Endocrinol 194:264-74. ARTICLE

Flood DEK, Fernandino JI2 and VS Langlois (2013) Thyroid hormones in male reproductive  development: Evidence for direct crosstalk between the androgen and thyroid hormone axes. Gen Comp Endocrinol  192:2-14. ARTICLE

Langlois VS and CJ Martyniuk1 (2013) Gene regulatory networks involved in early embryonic Silurana tropicalis development. Mech Dev 130:304-22. ARTICLE

Denyes MJ, Langlois VS, Rutter A1 and BA Zeeb1 (2012) The use of biochar to reduce soil PCB bioavailability to Cucurbita pepo and Eisenia fetida. Sci Total Environ  437:76-82. ARTICLE

Hayes TB2, DeSolla S3, Iguchi T2, Ingraham H2, Kestemont P2,  Kniewald J2, Kniewald Z2, Langlois VS, Luque EH2, Muñoz-de-Toro M2, Oka T2, Oliveira CA2, Suzawa M2, Tillit D2, Trudeau VL1, Victor-Costa1 AB and E Willingham2 (2011) Demasculinization and feminization of male gonads by atrazine: Consistent effects across vertebrate classes. J Steroid Biochem Mol Biol 127:64-73 ARTICLE

Langlois VS, Rutter A1 and BA Zeeb1 (2011) Activated carbon immobilizes residual polychlorinated biphenyls (PCBs) at contaminated terrestrial sites. J Environ Qual 40:1130-4. ARTICLE

Langlois VS, Duarte-Guterman P1 and VL Trudeau1 (2011) Expression profiles of reproduction- and thyroid-related transcripts in the brains of chemically-induced intersex frogs. Sex Dev 5:26-32. ARTICLE

Mennigen JA1, Lado WE1, Zamora JM1, Duarte-Guterman P1, Langlois VS, Metcalfe CD1, Chang JP1, Moon TW1 and VL Trudeau1 (2010) Fluoxetine disrupts the reproductive axis in sexually mature male goldfish, Carassius auratus. Aquat Toxicol 100:354-64. ARTICLE

Langlois VS, Zhang D1, Cooke GM3 and VL Trudeau1 (2010) Evolution of steroid 5-alpha-reductases and a comparison of their function with 5-beta-reductase. Gen Comp Endocrinol. 166:489-97. ARTICLE

Langlois VS, Carew AC, Pauli BD3, Wade MG3, Cooke GM3 and VL Trudeau1 (2010) Low levels of the herbicide atrazine disrupt Rana pipiens gonadal development and metamorphosis in outdoor mesocosms. Environ Health Perspect 118:552-7. ARTICLE

Langlois VS, Duarte-Guterman P1, Ing S, Pauli BD3, Cooke GM3 and VL Trudeau1 (2010) Fadrozole and finasteride exposures modulate sex steroid- and thyroid-related gene expression in Silurana (Xenopus) tropicalis early larval development. Gen Comp Endocrinol 166:417-427. ARTICLE

Zhang D1, Duarte-Guterman P1, Langlois VS and VL Trudeau1 (2010) Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development Comp Biochem Physiol C Tox Pharmacol 152:202-6. ARTICLE

Duarte-Guterman P1, Langlois VS, Pauli BD3 and VL Trudeau1 (2010) Expression and T3 regulation of thyroid- and sex steroid-related genes during Silurana (Xenopus) tropicalis early development. Gen Comp Endocrinol 166:428-435. ARTICLE

Duarte-Guterman P1, Langlois VS, Hodgkinson KM, Pauli BD3, Wade MG3, Cooke GM3 and VL Trudeau1 (2009) The aromatase inhibitor fadrozole and the 5-reductase inhibitor finasteride affect gonadal differentiation and gene expression in the frog Silurana tropicalis. Sex Dev 3:333-41. ARTICLE

Croteau MC1, Renner VE1, Archibald F1, Langlois VS, Cahn J1, Ridal J1, Trudeau VL1, DRS Lean1 (2007) Investigation of pathogenic Escherichia coli and microbial pathogens in pulp and paper mill biosolids. Water Environ Res 79:1050-6. ARTICLE